Status:
UNKNOWN
Study on Effect of Intestinal Microbiota Transplantation in Hepatitis B Virus Induced Cirrhosis
Lead Sponsor:
Zhongshan Hospital Xiamen University
Conditions:
Cirrhosis, Liver
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
Chronic hepatitis B (CHB) is a common infectious disease affecting up to 2 billion people worldwide. Around 650 thousand people died of liver failure, cirrhosis and primary liver cancer caused by chro...
Detailed Description
A group of 60 patients with HBV induced cirrhosis will be recruited for study, which involved a 4 times IMT with gastroduodenoscopy and the time interval is generally 2 weeks. Participants can keep ta...
Eligibility Criteria
Inclusion
- Written informed consent/assent as appropriate, able to keep treatment
- 18 to 50 years of age
- Chronic hepatitis B, definitely diagnosed as hepatic fibrosis/cirrhosis through Fibroscan/Biopsy of liver biopsy
Exclusion
- Drug treatment(immunosuppressive drugs, biological agents, high dose vitamins or other immunosuppressive drugs
- Other immune related diseases
- Gastrointestinal organic lesions such as gastroesophageal reflux disease, inflammatory bowel disease, intestinal tumor
- Medical or social condition which in the opinion of the principal investigator would interfere with or prevent regular follow up
- Participating in other clinical trials
Key Trial Info
Start Date :
October 31 2016
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2020
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03437876
Start Date
October 31 2016
End Date
December 1 2020
Last Update
February 19 2018
Active Locations (1)
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1
Zhongshan Hospital Affiliated to Xiamen University
Xiamen, Fujian, China, 361000