Status:
COMPLETED
The INTER-CARDIO Study: The Impact of Commonly Consumed Fat on Cardiovascular Health; a Randomised Controlled Trial
Lead Sponsor:
King's College London
Conditions:
Healthy Adults
Eligibility:
All Genders
35-75 years
Phase:
NA
Brief Summary
The purpose of this study is to investigate whether there are differences in postprandial cardiometabolic metabolic indices following interesterified fats used commercially versus application appropri...
Detailed Description
Aim: The current study aims to investigate the acute effects of commercially available interesterified fat versus versus application appropriate non- interesterifed alternative fat on 8 h postprandial...
Eligibility Criteria
Inclusion
- Males and females aged 35-75 years
- Healthy (free of diagnosed diseases listed in exclusion criteria)
- Able to understand the information sheet and willing to comply with study protocol
- Able to give informed consent
Exclusion
- Medical history of myocardial infarction, angina, thrombosis, stroke, cancer, liver or bowel disease or diabetes
- Body mass index \< 20 kg/m2 or \> 35 kg/m2
- Plasma cholesterol ≥7.5 mmol/L
- Plasma triacylglycerol \> 3 mmol/L
- Plasma glucose \> 7 mmol/L
- Blood pressure ≥140/90 mmHg
- Current use of antihypertensive or lipid lowering medications
- Alcohol intake exceeding a moderate intake (\> 28 units per week)
- Current cigarette smoker (or quit within the last 6 months)
- ≥ 20% 10-year risk of CVD as calculated using a risk calculator
Key Trial Info
Start Date :
July 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 31 2019
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT03438084
Start Date
July 1 2018
End Date
October 31 2019
Last Update
January 27 2020
Active Locations (2)
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1
Department of Nutritional Sciences, Faculty of Life Sciences and Medicine, Kings College London
London, United Kingdom, SE1 9NH
2
King's College London
London, United Kingdom, SE1 9NH