Status:
UNKNOWN
Effect of Intermittent Infusion Versus Continuous Infusion of Vancomycin on Kidney Failure in Critically Ill Patients
Lead Sponsor:
University of Sao Paulo
Conditions:
Gram-Positive Bacterial Infections
Nephrotoxicity
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
This is a randomized, controlled multicenter clinical trial. The purpose of this study is to compare the continuous infusion of vancomycin with intermittent infusion regarding the effectiveness to rea...
Detailed Description
The vancomycin is a glycopeptide antimicrobial which has been used for 50 years against gram-positive microorganisms and remains effective against multiresistant bacteria as the methicillin resistant ...
Eligibility Criteria
Inclusion
- Critically ill patients
- Treatment with vancomycin
- Preserved renal function.
Exclusion
- Cystic fibrosis
- Chronic renal failure
- Acute renal failure
- Having received vancomycin in the last 24 hours
- Vancomycin hypersensibility
Key Trial Info
Start Date :
April 28 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2022
Estimated Enrollment :
222 Patients enrolled
Trial Details
Trial ID
NCT03438214
Start Date
April 28 2018
End Date
December 1 2022
Last Update
April 5 2018
Active Locations (1)
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1
Faculty of Medicine University os São Paulo
São Paulo, São Paulo, Brazil, 01246-903