Status:
COMPLETED
Large Sample PD Patients and Healthy Controls
Lead Sponsor:
Xuanwu Hospital, Beijing
Conditions:
Neuro-Degenerative Disease
Eligibility:
All Genders
50-70 years
Brief Summary
Resting-state functional magnetic resonance imaging (RS-fMRI) has frequently been used to investigate local spontaneous brain activity in Parkinson's disease (PD) in a whole-brain, voxel-wise manner. ...
Detailed Description
Seed-based d Mapping (formerly Signed Differential Mapping, SDM) software (version 5.141 for Windows) (www.sdmproject.com) was used for meta-analysis. For the validation, fMRI data were acquired on a...
Eligibility Criteria
Inclusion
- The PD diagnoses were based on the UK Parkinson's Disease Society Brain Bank Clinical Diagnostic Criteria. Patients were assessed using the UPDRS III and Hoehn and Yahr disability scale.
Exclusion
- 1\. history of head trauma, 2. substance abuse, 3. psychiatric disorder. For healthy controls, additional exclusion criteria included
- any history of neuropsychiatric disorders.
Key Trial Info
Start Date :
May 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2016
Estimated Enrollment :
132 Patients enrolled
Trial Details
Trial ID
NCT03439163
Start Date
May 1 2011
End Date
January 1 2016
Last Update
February 26 2018
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