Status:
SUSPENDED
Magnesium for Shivering in Epidural Lidocaine Deliveries
Lead Sponsor:
University of British Columbia
Conditions:
Anesthesia
Eligibility:
FEMALE
19+ years
Phase:
NA
Brief Summary
Magnesium has been shown to decrease the shivering experienced from neuraxial anesthesia. This study aims to investigate whether magnesium decreases the shivering experienced in parturients undergoing...
Detailed Description
Women who have epidurals in place and go on to require a Cesarean delivery typically have their epidurals 'topped-up' with a fast onset local anesthetic to ensure the lower body is fully numb for surg...
Eligibility Criteria
Inclusion
- Gestational age of ≥37 weeks
- Women who are ≥ 19 years old
- Women undergoing Cesarean delivery under lidocaine top-up via a preexisting epidural catheter inserted for labor analgesia
- American Society of Anesthesiologist (ASA) Physical Status class 1 or 2
Exclusion
- Emergency Cesarean delivery with limited time for informed consent
- Women who have received MgSO4 prior to study enrollment
- Indication for alternative mode of anesthesia for Cesarean delivery (e.g., general anesthesia)
- Medical conditions or medications that could lead to tremor or shivering. (e.g., movement disorder, untreated thyroid disease) or mask tremor or shivering (e.g., beta-blocker, benzodiazepine, anticonvulsants)
- Active shivering at time of recruitment
- Inability to read and understand English for the purpose of informed consent
- Contraindications to receiving MgSO4 (hypersensitivity reactions, respiratory rate \<16breaths/min, absent reflexes, urine output \<100 mL during the previous 4 hours, renal failure, or hypocalcemia)
- History of previous postpartum hemorrhage
Key Trial Info
Start Date :
June 11 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2021
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT03439358
Start Date
June 11 2018
End Date
September 1 2021
Last Update
February 26 2021
Active Locations (1)
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1
BC Women's Hospital
Vancouver, British Columbia, Canada, V6H 3N1