Status:
COMPLETED
NRD to Predict COPD Exacerbations at Home
Lead Sponsor:
Guy's and St Thomas' NHS Foundation Trust
Conditions:
Chronic Obstructive Pulmonary Disease
Eligibility:
All Genders
40-80 years
Brief Summary
COPD is a common, serious disease and is a major burden on patients and the National Health Service. Patients with COPD can develop worsening of their symptoms, known as an exacerbation, which can be ...
Detailed Description
Introduction COPD is a common and serious disease, and is a major burden on patients and the National Health Service. Current markers to detect and monitor exacerbations and response to treatment are...
Eligibility Criteria
Inclusion
- Age 40-80 years
- Patients hospitalized with a primary diagnosis of an acute exacerbation of COPD
- Body mass index (BMI) ≤ 35 kg/m2
- Cognitively and linguistically able to follow instructions given in English and provide informed consent
- To be discharged to home following the hospitalization
- Patient lives in the catchment area served by the Integrated Respiratory Team at Guy's and St Thomas' NHS Foundation Trust in a home environment deemed safe by the investigators to perform home assessments
Exclusion
- Previous home PAP (CPAP or NIV) therapy use within the past year, or post-discharge
- Allergies to latex, metals or local anaesthetic agents
- Wound or inflamed skin at parasternal location (2nd intercostal space)
- History of skin allergies or sensitivity to cosmetics and lotions
- Psychological and social factors that would impair compliance with study protocol and schedule
- Any major non-COPD chronic disease or condition, such as severe heart failure (LVEF\<30%), malignancy (active treatment and palliation), end stage renal failure/dialysis, significant neuromuscular disease (e.g. NMD, MD) determined by review of medical history and / or patient reported medical history that may contribute significantly to risk of readmission, as determined by PI
- Length of stay ≤ 24 hours
- Planned travel away from home within the 30 day post discharge period
Key Trial Info
Start Date :
February 13 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 6 2019
Estimated Enrollment :
23 Patients enrolled
Trial Details
Trial ID
NCT03443505
Start Date
February 13 2018
End Date
June 6 2019
Last Update
October 17 2019
Active Locations (1)
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1
Guys and St Thomas NHS Foundation Trust
London, United Kingdom, SE1 7EH