Status:
WITHDRAWN
Early Diagnosis and Treatment of Sleep Disordered Breathing in Lung Cancer
Lead Sponsor:
Mark M. Fuster, MD
Conditions:
Lung Cancer
Eligibility:
All Genders
18+ years
Brief Summary
Sleep-disordered breathing at night is a common medical problem. It leads to daytime fatigue, impairment in concentration and daily activities, and a higher risk of cardiovascular disease and life-thr...
Eligibility Criteria
Inclusion
- Diagnosis of lung cancer in one of 2 sub-types:
- newly diagnosed early-stage tumor
- advanced-stage lung tumor undergoing serial contrast-CT imaging according to standard of care
- Diagnosis of a metastatic carcinomatous mass in the lung
- Positive study for sleep-disordered breathing (SDB) with intermittent hypoxia (IH) and clinical recommendation for CPAP
- Ability and willingness to undergo baseline and repeat perfusion-CT imaging following 3- to 4 weeks of CPAP therapy for SDB (regardless of CPAP compliance).
- Note: Participants will undergo sleep study and receive CPAP therapy as a part of routine care.
Exclusion
- Lung cancer with a negative sleep study (i.e., no SDB)
- History of radio-contrast allergy
- At excessive risk for contrast nephropathy (following standard radiology renal-risk criteria)
- Pregnancy
Key Trial Info
Start Date :
November 17 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 13 2019
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT03443908
Start Date
November 17 2017
End Date
May 13 2019
Last Update
December 17 2021
Active Locations (1)
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1
UC San Diego Moores Cancer Center
La Jolla, California, United States, 92093