Status:
COMPLETED
Oxygenation Instability and Maturation of Control of Breathing in Premature Infants
Lead Sponsor:
University of Miami
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Infant,Premature
Eligibility:
All Genders
Brief Summary
Premature infants present with significant oxygenation instability in the form of frequent spontaneous episodes of hypoxemia during the first weeks after birth. These infants are also exposed to hyper...
Detailed Description
Most extreme premature infants present with respiratory failure due to altered lung function compounded by breathing instability due to an immature respiratory control function. Premature infants pre...
Eligibility Criteria
Inclusion
- Premature infants born at 23 0/7- 28 6/7 weeks gestational age
- Postnatal age up to equivalent to 36 weeks postmenstrual age
- Requiring supplemental oxygen and/or receiving mechanical ventilation, CPAP, nasal ventilation or nasal cannula
Exclusion
- Severe congenital anomalies that may affect life expectancy or pulmonary or neurosensory development
- Severe CNS pathology that may alter respiratory control function
Key Trial Info
Start Date :
September 4 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 1 2023
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT03445689
Start Date
September 4 2018
End Date
November 1 2023
Last Update
March 18 2025
Active Locations (1)
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1
NICU at Holtz Children's Hospital
Miami, Florida, United States, 33136