Status:
WITHDRAWN
Epicardial Mini-Maze Versus Catheter Ablation for the Management of Persistent Atrial Fibrillation
Lead Sponsor:
The University of Texas Health Science Center, Houston
Conditions:
Persistent Atrial Fibrillation
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study will assess the efficacy of catheter ablation versus the Wolf Mini-Maze surgical ablation for rhythm control in patients with persistent afib.
Detailed Description
Higher success rates have been achieved after a single surgical ablation when compared to catheter ablation, however contiguous and transmural lesions are not always guaranteed. Even though, catheter...
Eligibility Criteria
Inclusion
- Persistent symptomatic AF with failure of at least 1 anti-arrhythmic drug
- Prior pulmonary vein isolation (PVI)
- CHA2DS2VASC \> 0
- Able to tolerate and compliant with oral anticoagulation with either Warfarin, dabigatran, rivoraxaban or apixiban
Exclusion
- Inability to follow-up as per protocol
- Prior valvular surgery or valve replacement
- Reversible cause for atrial fibrillation
- Currently on dialysis or renal replacement therapy
- Need for concomitant cardiac surgery
- History of MI or stroke ≤2 months prior to ablation
- Intolerance to oral anticoagulants
- Thrombus in the Left atrial appendage
Key Trial Info
Start Date :
June 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 18 2018
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT03446222
Start Date
June 1 2016
End Date
December 18 2018
Last Update
February 26 2018
Active Locations (1)
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1
The University of Texas Health Science Center at Houston
Houston, Texas, United States, 77030