Status:
COMPLETED
Early Initiation of High-flow Nasal Cannula Oxygen Therapy in Patients With Acute Respiratory Failure in the Emergency Department: A Before-after Study
Lead Sponsor:
Poitiers University Hospital
Collaborating Sponsors:
Centre Hospitalier de Niort
Conditions:
Acute Respiratory Failure
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The aim of the study is to compare the efficiency on respiratory failure regression of high-flow nasal oxygen therapy versus standard oxygen in patients admitted to the ED for de novo acute respirator...
Detailed Description
Prospective observational before-after study at the ED in two French centers. Selection of patients with acute hypoxemic respiratory failure at the ED. Application of oxygen strategy according to th...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- de novo acute respiratory failure cowith the following criteria: a respiratory rate \> 25 b/min, or signs of increased work of breathing.
- Main exclusion Criteria:
- cardiogenic pulmonary edema,
- acute exacerbation of chronic lung disease, respiratory acidosis (pH \< 7.35 and PaCO2 \> 50 mm Hg),
- hemodynamic instability
- Glasgow Coma Scale score of 12 points or less,
- an urgent need for endotracheal intubation,
Exclusion
Key Trial Info
Start Date :
December 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 30 2017
Estimated Enrollment :
102 Patients enrolled
Trial Details
Trial ID
NCT03447457
Start Date
December 1 2015
End Date
May 30 2017
Last Update
February 27 2018
Active Locations (2)
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1
CHG de Niort
Niort, France, 79000
2
CHU Poitiers
Poitiers, France, 86000