Status:
COMPLETED
Diet-Induced Variability in Appetite (DIVA)
Lead Sponsor:
University of Leeds
Collaborating Sponsors:
University of Illinois at Chicago
Conditions:
Overweight and Obesity
Eligibility:
FEMALE
18-55 years
Phase:
NA
Brief Summary
The aim of this study is to test the hypothesis that dietary weight loss (WL) through alternate day fasting (ADF) will enhance appetite control, health markers and wellbeing following WL compared to s...
Detailed Description
This is a proof of concept randomized controlled trial in which overweight/obese females will be randomised to a dietary weight loss intervention (ADF or CR) to achieve ≥5% WL. Behavioural measures of...
Eligibility Criteria
Inclusion
- Female participants aged between 18 and 55 years at the time of signing informed consent
- BMI of 25.0 - 34.9 kg/m2
Exclusion
- Significant health problems which in the opinion of the investigator, might jeopardise participant's safety or compliance with the protocol
- Currently enrolled in a weight loss programme or following a specific diet plan.
- History of eating disorders including binge eating.
- Taking any medication or supplements known to affect appetite or weight within the past month and/or during the study
- Pregnant, planning to become pregnant or breastfeeding
- History of anaphylaxis to food
- Known food allergies or food intolerance
- Smokers and those who have recently ceased smoking (\< 6 months)
- BMI \< 24.9 kg/m2 or \> 35 kg/m2
- Volunteers having lost significant amount of weight in the previous 6 months (± 4kg)
- Volunteers who exercise \> 3 days per week or have significantly changed their physical activity patterns in the past 6 months or who intend to change them during the study
- Participants receiving systemic or local treatment likely to interfere with evaluation of the study parameters
- Participants who work in appetite or feeding related areas.
- Participants who do shift work
Key Trial Info
Start Date :
March 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 12 2018
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT03447600
Start Date
March 1 2018
End Date
December 12 2018
Last Update
November 6 2020
Active Locations (1)
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1
University of Leeds
Leeds, West Yorkshire, United Kingdom, LS2 9JT