Status:
UNKNOWN
EUROpean Intracoronary Cooling Evaluation in Patients With ST-elevation Myocardial Infarction.
Lead Sponsor:
Catharina Ziekenhuis Eindhoven
Collaborating Sponsors:
Abbott
Golden Jubilee National Hospital
Conditions:
Acute Myocardial Infarction
Reperfusion Injury
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
In acute myocardial infarction, early restoration of epicardial and myocardial blood flow is of paramount importance to limit infarction size and create optimum conditions for favourable long-term out...
Eligibility Criteria
Inclusion
- Acute anterior wall ST-elevation myocardial infarction
- Total ST-segment deviation of at least 5 mm
- Presenting within 6 hours after onset of complaints
- TIMI 0 or 1 flow in the LAD
- Hemodynamically stable and in an acceptable clinical condition
- Able to give informed consent
Exclusion
- Age \<18 year or \>80 year
- Cardiogenic shock or hemodynamically unstable patients
- Patients with previous myocardial infarction in the culprit artery of with previous bypass surgery
- Very tortuous or calcified coronary arteries
- Complex or long-lasting primary PCI expected
- Severe concomitant disease or conditions with a life expectancy of less than one year
- Inability to understand and give informed consent
- Known contra-indication for MRI
- Pregnancy
- Severe conduction disturbances necessitating implantation of temporary pacemaker
Key Trial Info
Start Date :
January 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2023
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT03447834
Start Date
January 1 2019
End Date
June 30 2023
Last Update
July 6 2022
Active Locations (1)
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1
Catharina hospital
Eindhoven, North Brabant, Netherlands, 5623 EJ