Status:

ACTIVE_NOT_RECRUITING

Comprehensive Lifestyle Change To Prevent Breast Cancer

Lead Sponsor:

M.D. Anderson Cancer Center

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Premenopausal

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

This trial studies how well comprehensive lifestyle change works in preventing patients from breast cancer. A program including dietary recommendations, physical activity, stress management and mindfu...

Detailed Description

PRIMARY OBJECTIVES: I. Assess the feasibility of a randomized controlled trial involving a mobile, standardized, comprehensive integrative oncology (IO) prevention program. SECONDARY OBJECTIVES: I....

Eligibility Criteria

Inclusion

  • Able to read, write, and speak English
  • Premenopausal
  • A body mass index (BMI) \>= 25
  • Have intact breasts and ovaries
  • Able to provide informed consent to participate in the study
  • Meet all the following criteria related to lifestyle: a) consume less than 3 servings of vegetables (excluding any fried servings) and 1 serving of fruit (not including juice)/day; b) engage in less than 150 minutes moderate/vigorous intensity activity per week, defined as anything that causes small increases in breathing or heart rate for a sustained amount of time (e.g., brisk walking, bicycling); c) engage in a mind-body practice less once per week
  • Able mentally and physically to participate in interventions in this study (Note: If there are one or more positive responses to the Physical Activity Readiness Questionnaire \[PARQ\], then a physician-release for exercise is required prior to obtaining consent)
  • Access to internet connection
  • Able to come to University of Texas (UT) MD Anderson for the orientation and assessment sessions

Exclusion

  • Any personal history of cancer, including ductal carcinoma in situ (DCIS) and not including non-melanoma skin cancers
  • Any major thought disorder (e.g., schizophrenia, dementia)
  • Communication barriers (e.g. hard of hearing)
  • Poorly or uncontrolled diabetes in the opinion of the physician(s)
  • Being pregnant or planning on becoming pregnant within the next year
  • Contemplating any new pharmacologic/hormonal or prophylactic surgical intervention for breast cancer prevention within the next year (Note: Individuals taking tamoxifen, arimidex or other hormonal prevention strategies at time of consent will be eligible)

Key Trial Info

Start Date :

April 4 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 31 2027

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT03448003

Start Date

April 4 2019

End Date

August 31 2027

Last Update

August 15 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

M D Anderson Cancer Center

Houston, Texas, United States, 77030

Comprehensive Lifestyle Change To Prevent Breast Cancer | DecenTrialz