Status:

WITHDRAWN

rTMS for the Treatment of Primary Progressive Aphasia: A Randomized Controlled Trial

Lead Sponsor:

Peking Union Medical College Hospital

Conditions:

Aphasia, Primary Progressive

Repetitive Transcranical Magnetic Stimulation

Eligibility:

All Genders

35-75 years

Phase:

NA

Brief Summary

The primary progressive aphasia (PPA) is a neurodegenerative condition characterized by a gradual, irreversible decline of language function (Mesulam, 2001). There are no known treatments for PPA so f...

Eligibility Criteria

Inclusion

  • All participants had also been evaluated previously by a behavioral neurologist at the Peking Union Medical College Hospital and had been clinically diagnosed with a variant of PPA.

Exclusion

  • Scored below 15 on the mini-mental state exam (MMSE) due to concerns that global cognitive impairment might preclude their ability to follow the directions and interfere with task performance.
  • Had a history of seizures or unexplained loss of consciousness, pregnancy, surgical breach of the skull, or any other medical or surgical contraindication to receiving noninvasive brain stimulation.
  • Is unable to complete the treatment and evaluations

Key Trial Info

Start Date :

March 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2021

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT03448133

Start Date

March 1 2018

End Date

December 31 2021

Last Update

June 5 2020

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