Status:
COMPLETED
Role of Branched-chain Amino Acids Infusion as Adjunct Therapy Post Liver Surgery for Patients in Intensive Care Unit
Lead Sponsor:
National Hepatology & Tropical Medicine Research Institute
Conditions:
Liver Function Post BCAA Infusion
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate the impact of intravenous BCAAs infusion as adjunct therapy post liver surgery in intensive care unit (ICU).
Detailed Description
Patients will be enrolled in the study\&randomly assigned in a 1:1 manner to receive either intravenous (IV) BCAAs in a dose of 0.5-1gm/Kg/day for at least 48hours up to maximum 5 days immediately pos...
Eligibility Criteria
Inclusion
- The subjects are adults aged between 18\& 75years who are admitted to the ICU of National Hepatology \& Tropical Medicine Research Institute (NHTMRI) post liver surgery e.g. hepatocellular carcinoma, liver hemangioma, hydatid resection, segmentectomy, partial hepatectomy as in donor for living donated liver transplant.
Exclusion
- if pregnant.
- hemodynamic instability requiring circulatory support.
- need for dose of BCAAs \> 1gm/Kg/day or \< 0.5 gm/Kg/day.
- severe malnutrition; body mass index (BMI \< 16).
Key Trial Info
Start Date :
March 15 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 10 2020
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03448848
Start Date
March 15 2018
End Date
September 10 2020
Last Update
February 21 2021
Active Locations (1)
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1
NHTMRI
Cairo, Egypt