Status:
COMPLETED
Renal Artery Dopplers in Twin Twin Transfusion Syndrome
Lead Sponsor:
Columbia University
Conditions:
Twin Twin Transfusion Syndrome
Eligibility:
FEMALE
Brief Summary
Twin-twin transfusion syndrome (TTTS) is a complication affecting 10-15% of monochorionic, diamniotic (MCDA) twin pregnancies. Unevenly distributed blood flow across a shared placental circulation res...
Detailed Description
TTTS, which complicates 10-15% of MCDA twin pregnancies, is characterized by a net imbalance of volume between twins, mediated through abnormal placental blood vessel anastomoses that connect the two ...
Eligibility Criteria
Inclusion
- pregnant women with monochorionic / diamniotic (MCDA) twin pregnancies with and without twin-twin transfusion syndrome (TTTS)
- greater than 14 weeks gestation
Exclusion
- higher-order multiple gestation
- sonographic evidence of a major structural fetal anomaly (exceptions to this structural fetal anomaly exclusion are acquired recipient twin cardiac changes that are known to be associated with TTTS - these cases may be considered for study inclusion)
Key Trial Info
Start Date :
September 9 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 30 2018
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT03449823
Start Date
September 9 2016
End Date
June 30 2018
Last Update
July 18 2018
Active Locations (1)
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1
Columbia University Medical Center
New York, New York, United States, 10032