Status:
COMPLETED
Functional Magnetic Resonance Imaging (fMRI) Investigation Into Compulsivity in Anorexia
Lead Sponsor:
University of Oxford
Conditions:
Anorexia Nervosa in Remission (Disorder)
Compulsive Behavior
Eligibility:
FEMALE
18-40 years
Phase:
NA
Brief Summary
The investigators will examine compulsivity in those who have recovered from anorexia nervosa, using a multi-modal MRI study. The neural activation of key fronto-striatal areas will be explored using ...
Detailed Description
The investigators will perform four different MRI (Magnetic Resonance Imaging) scans during one scanning session on those who have recovered from anorexia nervosa (AN) and healthy controls. Participa...
Eligibility Criteria
Inclusion
- Able and willing to give informed consent
- BMI over 18.5 and has remained so for the last year
- Score lower than mean+1 standard deviation of global mean scores for young women on the EDE
- Fluent English speaker
- Former diagnosis of anorexia nervosa in relevant group
Exclusion
- Any current diagnosis of a psychiatric disorder which in the investigator's opinion could impact study results (e.g. significant depression, anxiety or OCD).
- Any current psychotropic medications.
- Eyesight problems that would prohibit participating in a task-fMRI study.
- Current regular cigarette smoking of over 5 cigarettes per day.
- Recent use of illicit drugs.
- Alcohol intake which indicates an element of alcohol abuse; or unwillingness to refrain from drinking the night before the study visit.
- Any contraindications to MRI scanning (including claustrophobia).
- Participant is pregnant or breast-feeding.
Key Trial Info
Start Date :
May 5 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 7 2018
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03450239
Start Date
May 5 2017
End Date
February 7 2018
Last Update
April 5 2018
Active Locations (1)
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1
Department of Psychiatry, University of Oxford
Oxford, Oxfordshire, United Kingdom, OX3 7JX