Status:
COMPLETED
Eating Concerns and Compulsivity
Lead Sponsor:
University of Oxford
Conditions:
Anorexia Nervosa in Remission
Eating Disorder
Eligibility:
FEMALE
18-45 years
Phase:
NA
Brief Summary
This study uses a computational task to examine differences in adaptive learning to both rewards and punishments between three groups: those who have recovered from anorexia nervosa, those who score h...
Detailed Description
This study involves using a novel computational task (the volatility task, designed by Dr Michael Browning) to examine differences in adaptive learning in terms of sensitivity to environmental change ...
Eligibility Criteria
Inclusion
- Participant is willing and able to give informed consent for participation in the study.
- Females aged 18 to 45 years.
- BMI over 18.5 and has remained so for the last year.
- Participant is a fluent English speaker. Inclusion: recovered from anorexia
- Past formal diagnosis of AN (defined by DSM-5 criteria).
- Fully recovered: Score must be below 2.767 on the EDE-Q, below 16 on the CIA, and below 20 on the EAT-26 or partially recovered: scores may be above 2.767, 16 and 20 respectively.
- Inclusion: high scoring on EAT-26
- Score above 20 on the EAT-26 questionnaire. Inclusion: healthy control
- Score below 2.767 on the EDE-Q, below 16 on the CIA, and below 20 on the EAT-26.
Exclusion
- Any current diagnosis of a psychiatric disorder which in the investigator's opinion could impact study results (e.g. significant depression, anxiety or OCD).
- Any current psychotropic medications.
- Current regular cigarette smoking of over 5 cigarettes per day.
- Recent use of illicit drugs.
- Alcohol intake which indicates an element of alcohol abuse; or unwillingness to refrain from drinking the night before the study visit.
- Exclusion for high scoring EAT-26
- • A former formal diagnosis of an eating disorder. Note that in this group a current diagnosis of EDNOS will not be an exclusion criterion.
Key Trial Info
Start Date :
August 18 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2018
Estimated Enrollment :
82 Patients enrolled
Trial Details
Trial ID
NCT03450291
Start Date
August 18 2017
End Date
June 1 2018
Last Update
July 6 2018
Active Locations (1)
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1
Department of Psychiatry, University of Oxford
Oxford, Oxfordshire, United Kingdom, OX3 7JX