Status:
COMPLETED
Effect of Lifitegrast on Dry Eye Disease Signs and Symptoms
Lead Sponsor:
Lifelong Vision Foundation
Conditions:
Dry Eye
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
To determine whether a fall in tear osmolarity precedes improvement in symptoms and signs of dry eye in dry eye patients treated topically with 5% lifitegrast drops for 3 months.
Detailed Description
A longitudinal, single-arm, prospective study will recruit up to 30 subjects with moderate to severe dry eye disease. Subjects will be \>18 years of age, diagnosed with moderate to severe dry eye (tea...
Eligibility Criteria
Inclusion
- Tear Osmolarity \> 320 mOsm/L
- VAS eye dryness \> 40
- No other ocular pathology
- No contact lens wear
- Not currently on T cell modulator
- No change in therapy in last 2 months
- Willingness to adhere to therapy and study visits
- Patients qualified for prescription of lifitegrast drops
Exclusion
- Contact lens use
- Eye surgery in Past 6 months
- Use of tear supplements in past 2 hours
Key Trial Info
Start Date :
December 12 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 15 2018
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03451396
Start Date
December 12 2016
End Date
March 15 2018
Last Update
March 19 2018
Active Locations (1)
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1
Lifelong Vision Foundation
Chesterfield, Missouri, United States, 63017