Status:
UNKNOWN
Effects of Acute Intermittent Hypoxia on Brain Function Imaging and Systemic Inflammation
Lead Sponsor:
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Conditions:
Hypoxemia
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
Effects of acute intermittent hypoxia on brain function imaging and systemic inflammation Patients with obstructive sleep apnea (OSAS) may have neurological cognitive impairment. The reason is not cl...
Detailed Description
In this study, the potential risks to subjects and their corresponding prevention measures: 1. During the test, the volunteers may feel mild sleepiness due to oxygen. (Countermeasures: the subjects h...
Eligibility Criteria
Inclusion
- Healthy volunteers between 18 and 50 years old, no physical abnormalities
- Without both smoking and drinking habits
- Without the following symptoms: heart, lung, liver, kidney, and thyroid diseases; neuropsychiatric disorders, diabetes history; histories of craniocerebral surgery and tumor disease; recent acute infectious disease (2 weeks); diseases of chronic systemic infection and inflammation
- BMI index in the normal range
- Without snoring and sleep apnea
- No metal in vivo implantation
Exclusion
- Diseases such as OSAS or other sleep apnea
- Recent craniocerebral trauma (1 month)
- Alcohol abuse and psychotropic drugs
- EKG checking abnormality or previous history of chest tightness palpitations
Key Trial Info
Start Date :
November 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2023
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT03453697
Start Date
November 1 2020
End Date
November 1 2023
Last Update
April 9 2019
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