Status:
UNKNOWN
NMES to Prevent Respiratory Muscle Atrophy in Mechanically Ventilated Patients
Lead Sponsor:
University Medical Center Nijmegen
Collaborating Sponsors:
Liberate Medical
Amsterdam UMC, location VUmc
Conditions:
Mechanical Ventilation Complication
Neuromuscular Electrical Stimulation
Eligibility:
All Genders
18-99 years
Phase:
NA
Brief Summary
Patients requiring prolonged time on the ventilator are susceptible to a wide range of clinical complications and excess mortality. It is therefore imperative for them to wean at the earliest possible...
Detailed Description
Approximately 30-40% of intubated patients at the intensive care unit (ICU) take more than one attempt to wean from mechanical ventilation (MV). 6-14% of intubated patients take longer than 7 days to ...
Eligibility Criteria
Inclusion
- age \> 18 year
- invasive mechanical ventilation less than 72 hours
- expected duration of MV after inclusion \> 72 hours
Exclusion
- no clearly visible separate layers of the abdominal wall muscles (external oblique, internal oblique and transverse abdominal muscles), assessed with ultrasound during routine care
- cardiac pacemaker
- congenital myopathies and/or existing central or peripheral neuropathies
- refractory epilepsy
- recent abdominal surgery within four weeks prior to study inclusion
- body mass index (BMI) greater than 35 kg/m2
- pregnancy
Key Trial Info
Start Date :
March 9 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2018
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT03453944
Start Date
March 9 2017
End Date
December 31 2018
Last Update
March 5 2018
Active Locations (3)
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1
UMC Nijmegen
Nijmegen, Gelderland, Netherlands, 6525 GA
2
Canisius Wilhelmina Hospital
Nijmegen, Gelderland, Netherlands, 6532 SZ
3
VU University Medical Center
Amsterdam, North Holland, Netherlands, 1081 HV