Status:
UNKNOWN
Efficacy of Doxycycline in the Treatment of Early Stages of Mycosis Fungoides
Lead Sponsor:
Cairo University
Conditions:
Lymphoma
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
Current study aims at assessing the efficacy of doxycycline as a potential treatment modality for early stages of MF.
Detailed Description
Objectives Objective is to evaluate the efficacy of doxycycline in treatment of early stages of mycosis fungoides (IA, IB and IIA) and to assess its apoptotic enhancing effect by studying the express...
Eligibility Criteria
Inclusion
- Adults (above 18) of either sex with established diagnosis of classic MF
Exclusion
- Any variant of MF other than the classic variant.
- Advanced stages of classic MF: Stage IIb, III or IV.
- Pregnant and lactating females.
- Patients with autoimmune diseases e.g. SLE
- Patients with solid or hematological malignancies e.g. breast cancer, leukemia, etc.
- Patients with any contraindications for doxycycline (eg: liver disease, kidney disease, photosensitivity, peptic ulcer or patients receiving systemic retinoids).
- Patients with any contraindication to phototherapy (eg: any other skin cancers or photosensitivity); or to psoralen (eg: liver disease)
Key Trial Info
Start Date :
March 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2019
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03454945
Start Date
March 1 2017
End Date
April 1 2019
Last Update
August 23 2018
Active Locations (2)
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1
Dermatology departement
Cairo, Egypt, 11562
2
Dermatology department
Cairo, Egypt, 11562