Status:

COMPLETED

Dose-Response Relationship of Ambulatory Load and Cartilage - Pilot Study

Lead Sponsor:

University Hospital, Basel, Switzerland

Collaborating Sponsors:

University of Erlangen-Nürnberg

Conditions:

Healthy

Eligibility:

All Genders

18-30 years

Phase:

NA

Brief Summary

The research question is if there is a dose-response relationship between blood biomarkers for articular cartilage and the magnitude of physiological load. To investigate this load induced biomarker c...

Detailed Description

The current state of research in the field and of our own research clearly shows that the in vivo mechanobiology of articular cartilage is poorly understood. Previous results of changes in cartilage b...

Eligibility Criteria

Inclusion

  • Age between 18 and 30 years
  • being physically active (\> 2/week)
  • body mass index (BMI) \<30 kg/m2

Exclusion

  • previous knee injury
  • neuromuscular condition affecting gait

Key Trial Info

Start Date :

July 5 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 31 2019

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT03455010

Start Date

July 5 2017

End Date

July 31 2019

Last Update

September 18 2019

Active Locations (1)

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1

University Hospital Basel

Basel, Canton of Basel-City, Switzerland, 4031