Status:
COMPLETED
Fluid Management Surgical Patients in Intensive Care Unit.
Lead Sponsor:
National Hepatology & Tropical Medicine Research Institute
Conditions:
Post Operative Fluid Management
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The aim of this study is to evaluate the efficacy of lactate clearance (LCR) versus central venous oxygen saturation (ScVO2) to guide fluid management for post-operative patients in the intensive care...
Detailed Description
Sixty patients will be randomly assigned in a 1:1 manner into two groups; (group A= thirty patients = ScVO2) \& (group B = thirty patients =lactate clearance). Fluid therapy will be initiated in each ...
Eligibility Criteria
Inclusion
- Patients who are admitted to the intensive care unit of National Hepatology \& Tropical Medicine Research Institute (NHTMRI) post intra-abdominal surgical intervention.
Exclusion
- Patients will be excluded from the study if they have severe liver impairment (child-Pugh C15), septic shock or hemodynamic instability requiring high dose circulatory support e.g. \> 2ug/min noradrenaline as it will impair lactate clearance \&/or central venous oxygen saturation normalization, advanced heart failure, central venous pressure (CVP) ≥ 18cmH2O as it will limit fluid therapy, severe hypothermia (\< 28◦ C) as it will induce lactate production.
Key Trial Info
Start Date :
August 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 15 2020
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03455296
Start Date
August 1 2018
End Date
May 15 2020
Last Update
March 19 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
NHTMRI
Cairo, Egypt