Status:
UNKNOWN
Effect of CPAP Therapy on LPR Among Patients With OSAS
Lead Sponsor:
Assiut University
Conditions:
Laryngopharyngeal Reflux
Obstructive Sleep Apnea
Eligibility:
All Genders
18+ years
Brief Summary
This study will investigate the changes in the reflux symptom index (RSI) and reflux finding score (RFS) among patients with obstructive sleep apnea after regular humidified CPAP therapy. Since these ...
Eligibility Criteria
Inclusion
- Patients have to stop proton pump inhibitors (PPI) therapy 1 month before enrollment in the study.
- To be eligible as LPR patients in our study, patients must have presented a RSI score \> 13 and a RFS score \> 7. These thresholds were highly correlated with pathological pH monitoring (pH \< 4)
Exclusion
- Noncompliance for CPAP Use: According to the standard Medicare criteria to define CPAP compliance, the patients who demonstrated CPAP use ≥ 4 h/ night for ≥ 70% of the nights are considered compliant.
- Antireflux therapy during the period of the study.
Key Trial Info
Start Date :
May 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2021
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03455803
Start Date
May 1 2018
End Date
September 1 2021
Last Update
March 7 2018
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