Status:
UNKNOWN
Safety and Feasibility of Normothermic Machine Perfusion to Preserve and Evaluate Orphan Livers
Lead Sponsor:
The Cleveland Clinic
Conditions:
Liver Transplantation
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Orphan livers are organs that have been declined for clinical use by all centers due to their marginality. The current standard of care of liver preservation before transplant is cold storage. NMP may...
Detailed Description
This will be a single center prospective cohort pilot study. 30 livers that have been declined for clinical use by all centers due to their marginality will be preserved with NMP in 1-18 hours after c...
Eligibility Criteria
Inclusion
- Patients undergoing primary liver transplantation
- Age 18-75 years at the time of transplantation
- Willingness and ability to comply with the study procedures
- Signed Informed Consent Form
- For patients with hepatocellular carcinoma as indication for Orthoptic Liver Transplantation (OLT), tumor must be within Milan Criteria or down-staged to Milan Criteria.
Exclusion
- Recipient
Key Trial Info
Start Date :
March 12 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2023
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03456284
Start Date
March 12 2020
End Date
December 1 2023
Last Update
April 13 2023
Active Locations (1)
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1
Cleveland Clinic
Cleveland, Ohio, United States, 44195