Status:
COMPLETED
Treating Frailty in Lung Transplant Candidates (PREHAB)
Lead Sponsor:
University of California, San Francisco
Conditions:
Advanced Lung Disease
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
In this pilot project, 35 lung transplant candidates will be recruited to participate in a three month individualized home-based program focused on exercise and nutrition optimization. This pilot is d...
Detailed Description
Lung transplantation aims to extend survival, reduce disability, and improve health-related quality of life for persons suffering from advanced lung diseases. Despite rigorous candidacy screening prac...
Eligibility Criteria
Inclusion
- Adult lung transplant candidates in the UCSF Lung Transplant Program aged \>=50
- Ability to understand and speak English or lives with a family member who has the ability to understand and speak English.
- A diagnosis of chronic obstructive pulmonary disease (COPD) or pulmonary fibrosis (PF).
- A supplemental oxygen requirement with exercise that can be delivered safely at home using their home oxygen concentrator (as determined by clinically available six-minute walk distance test)
- Waitilisted or soon to be waitlisted for lung transplantation at UCSF
- Short Physical Performance Battery (SPBB) frailty score of 9 or less (range 0 - 12; lower scores = worse frailty).
- Must be an outpatient.
- Willing and able to come to UCSF Parnassus Campus for 1 day in-person training program.
Exclusion
- Inability to speak or understand English or does not live with a family member who has the abilty to understand and speak English.
- Subject does not possess home oxygen equipment (if supplemental oxygen is required for exercise)
- Already or soon to be enrolled in a traditional hospital based pulmonary rehabilitation program
- Lives alone.
- A diagnosis of primary or secondary pulmonary hypertension. Diagnosis will be determined by clinically available right heart catheterization pulmonary arterial mean pressure \>= 30 mm Hg or transthoracic echocardiogram pulmonary arterial systolic pressure \> 50 mm Hg or report of moderate right ventricular dysfunction or worse. These tests are performed as part of routine clinical care in the lung transplant program. Echocardiograms are repeated every 6 months while patients are listed for transplantation.
Key Trial Info
Start Date :
December 11 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 14 2017
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT03457545
Start Date
December 11 2015
End Date
December 14 2017
Last Update
March 7 2024
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