Status:
COMPLETED
RIPC and Platelet Activation on Platelet Activation During Cardiopulmonary Bypass
Lead Sponsor:
Seoul National University Hospital
Conditions:
Platelet Dysfunction
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
In this study, the investigators are going to investigate the effects of remote ischemic preconditioning on platelet activation in patients undergoing cardiac surgery with cardiopulmonary bypass.
Detailed Description
Previous studies reported that remote ischemic conditioning reduce platelet activation in patients with coronary artery disease or patients undergoing ablation for atrial fibrillation. Cardiac surgery...
Eligibility Criteria
Inclusion
- Patients undergoing cardiac surgery with cardiopulmonary bypass
Exclusion
- Preoperative left ventricle ejection fraction \< 30%, mechanical ventricular support
- Peripheral vascular disease
- Poorly controlled diabetes mellitus
- NSAIDs within 3 days
- iv heparin within 6 h
- low molecular weight heparin within 24 h
- platelet inhibitor within 24 h
- known thrombocytopenia
- End stage renal disease / hemodialysis
- Active infection
- Pregnancy
Key Trial Info
Start Date :
March 28 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 14 2019
Estimated Enrollment :
58 Patients enrolled
Trial Details
Trial ID
NCT03458351
Start Date
March 28 2018
End Date
August 14 2019
Last Update
October 15 2019
Active Locations (1)
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1
Seoul National University Hospital
Seoul, South Korea, 03080