Status:
COMPLETED
Nitrate Supplementation and Muscle Blood Flow
Lead Sponsor:
University of Iowa
Conditions:
Vasodilation
Blood Pressure
Eligibility:
All Genders
60-80 years
Phase:
NA
Brief Summary
The main purpose of this study is to evaluate the effects of an acute dose of dietary nitrate in the form of beetroot juice on skeletal muscle blood flow in response to dynamic knee extension exercise...
Detailed Description
Dietary nitrate (beetroot juice) is reduced to nitrite and nitric oxide within the digestive system of humans. Nitric oxide exerts potent vasodilator effects, which have been shown to reduce blood pre...
Eligibility Criteria
Inclusion
- Healthy older adults 60-80 years of age
Exclusion
- Hypertension,
- Smoking,
- Heart disease,
- Diabetes,
- Body mass index (BMI) ≥ 30 kg/m2,
- Autonomic disorders and other conditions that may alter blood pressure or vascular function
- Medications that might normally alter blood pressure or vascular function.
- Older women taking hormone replacement therapy medications.
Key Trial Info
Start Date :
October 10 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 8 2018
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT03459027
Start Date
October 10 2017
End Date
February 8 2018
Last Update
January 9 2019
Active Locations (1)
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1
Medical Education Building
Iowa City, Iowa, United States, 52242