Status:
COMPLETED
Effects of Infra- and Ultrasound on the Brain
Lead Sponsor:
Universitätsklinikum Hamburg-Eppendorf
Collaborating Sponsors:
European Union
Conditions:
Brain Function
Ultrasound
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
Findings in neuroscientific research show that the environment one lives in has measurable effects on brain morphology and functioning. Human exposure to airborne infra- and ultrasound has been consta...
Detailed Description
Regarding effects of infra- and ultrasound on the brain, a pioneer study demonstrated that exposure to non-audible infrasound was associated with changes of neural activity across several brain region...
Eligibility Criteria
Inclusion
- healthy participants
- age 18-40
- informed consent for all parts of the study (including MRT)
- none of the exclusion criteria (see below) fulfilled
- normal hearing
Exclusion
- age \< 18 or \> 40 years
- pregnancy or breastfeeding
- living with young children (0-3 years)
- pets in sleeping room (e.g. cats, dogs, rodents, reptiles)
- living at extremely loud/ noisy street
- tinnitus
- chronic disease/ infection of ENT region
- ear deformation/ ear surgery
- (partial) deafness
- hearing aid/ cochlea implant
- degenerative or inflammatory diseases of the central nervous system
- severe cognitive/ neuropsychological impairment
- severe pain syndrome or other severe organic diseases
- epilepsy
- (past or present) psychiatric disorders
- neurological disorders
- severe diabetic polyneuropathy
- malignancies/ cancer
- cardiac insufficiency
- arterial hypertension
- heart attack/ stroke
- severe hepatic or renal insufficiency
- diseases of the hemopoietic system
- alcoholism/ drug addiction
- medical history of severe allergic or toxic reactions
- current participation in drug trial
- doubts about legal capacity/ capability of understanding
- referral to institutions based on court/ official order
- treatment with centrally acting medication (e.g. antipsychotics, antiepileptics, antidepressants, etc.)
- non-removable metal pieces (aneurysm clips, artificial limbs, etc.) or implanted electronic devices (pacemaker, osmotic or other implanted pumps, cochlear implants, etc.)
- claustrophobia
- acute (respiratory) infection, physical uneasiness
- tattoos in the head region, permanent make-up
- non-removable piercings
Key Trial Info
Start Date :
May 31 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 15 2019
Estimated Enrollment :
63 Patients enrolled
Trial Details
Trial ID
NCT03459183
Start Date
May 31 2018
End Date
December 15 2019
Last Update
July 8 2020
Active Locations (1)
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1
Universitätsklinikum Hamburg-Eppendorf, Klinik und Poliklinik für Psychiatrie und Psychotherapie, Hamburg, Germany
Hamburg, Germany, 20246