Status:
UNKNOWN
Soft Peri-implant Tissue Around Different Abutment Materials
Lead Sponsor:
University of Roma La Sapienza
Collaborating Sponsors:
Max-Planck Institute of Molecular Cell Biology and Genetics
Conditions:
Dental Implant Failure Nos
Wound Heal
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
Soft tissue attachment to the implant surface serves as a biological seal preventing the development of inflammatory periimplant diseases (i.e. peri-implant mucositis and peri-implantitis).It occurs i...
Detailed Description
Dental implants are anchored in jawbone through a direct bonding between bone and the implant. Success and survival of an implant do, however, not depend solely on osseointegration. A soft tissue, whi...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- Absence of Systemic Diseases / Disorders
- Smoking ≤ 5 cigarettes per day
- Periodontally healthy or treated
- Full-mouth plaque score (FMPS) ≤ 15% at baseline
- Full-mouth bleeding score (FMBS) ≤ 15% at baseline
- Presence of edentulous space needing an all on four or all on six treatment with overdenture
- Width of the keratinized gingiva ≥ 2 at the level of the crest
Exclusion
- (I) • Pregnancy / lactation
- Use of systemic antibiotics in the last 3 months
- Use of systemic antibiotics as prophylaxis for endocarditis
- A chronically treated patient (i.e. 2 weeks or longer) with medicines known to affect periodontal tissues (e.g. phenytoin, calcium antagonists, cyclosporine, warfarin and non-steroidal anti-inflammatory drugs) the last month before starting the study
- Radiotherapy in the neck-head region
- HIV, TB, hepatitis or other infectious diseases
- Abuse with drugs or alcohol
- Smoked cigarettes\> 5 cigarettes per day
- Untreated periodontitis
- FMPS\> 15% at baseline
- FMBS\> 15% at baseline
- Implants with peri-implant history
- Width of keratinized tissue over crest \<2 mm
- Need for bone reconstruction around implants to be inserted
Key Trial Info
Start Date :
September 6 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2021
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT03459547
Start Date
September 6 2021
End Date
December 1 2021
Last Update
September 28 2021
Active Locations (1)
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1
Department of Oral and Maxillofacial Sciences. Section of Periodontics.Sapienza, University of Rome
Rome, Italy, 00161