Status:

UNKNOWN

Clinical Features, Outcome and Prognosis of Human Metapneumovirus (hMPV) Lower Respiratory Tract Infections in Adult Inpatients

Lead Sponsor:

Assistance Publique - Hôpitaux de Paris

Conditions:

Lower Resp Tract Infection

Human Metapneumovirus Infection

Eligibility:

All Genders

18+ years

Brief Summary

The human metapneumovirus (hMPV) was first described in 2001. It belongs to the paramyxovirus family and is genetically close to the Respiratory Syncytial Virus (RSV). hMPV has a seasonal epidemic pat...

Detailed Description

The human metapneumovirus (hMPV) was first described in 2001. It belongs to the paramyxovirus family (paramyxoviridae subfamily). hMPV is genetically close to the Respiratory Syncytial Virus (RSV). hM...

Eligibility Criteria

Inclusion

  • Adult (≥18 years old) inpatients with:
  • an acute lower respiratory tract infection, defined by the presence of two of the following criteria in the 5 days preceding hospital admission or during the present hospital stay : fever, cough, expectoration, exercise or rest dyspnea, crackles, tubal breath, signs of respiratory failure (respiratory rate higher than 30 per minute...), thoracic pain, oxygen therapy, mechanical ventilation;
  • a respiratory mPCR (upper respiratory tracts specimen such as nasopharyngeal swab or lower respiratory tract specimen such as tracheal or bronchial aspiration or bronchoalveolar lavage) positive for hMPV in the 5 days following hospital admission.

Exclusion

  • Patient already included in the study.

Key Trial Info

Start Date :

March 23 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 31 2019

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT03460171

Start Date

March 23 2018

End Date

July 31 2019

Last Update

July 24 2019

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Service de réanimation-Hôpital Tenon

Paris, France, 75020