Status:
COMPLETED
Prevalence of FODMAP Intolerance and JHS in FGID and Association With Microbiome, Dyssynergic Defecation and Dietary Intervention
Lead Sponsor:
University of Zurich
Conditions:
Functional Gastrointestinal Disorders
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
Irritable bowel syndrome (IBS) is a disorder of gastrointestinal function characterized by abdominal symptoms and pain associated with alterations in bowel habit. The condition impacts on the quality ...
Detailed Description
Functional gastrointestinal disorders (FGID) are common in the general population. Symptoms such as pain, nausea, bloating, diarrhea or constipation may occur. Irritable bowel syndrome (IBS) is the mo...
Eligibility Criteria
Inclusion
- Inclusion criteria for FGID patients:
- Functional bowel disease as per physician's diagnosis (medical judgement) and Rome IV criteria
- Signed Informed Consent after being informed
- Age 18-60 years
- Inclusion criteria for hepatology control cohort:
- Signed Informed Consent after being informed
- Age 18-60 years
- Patient in the ambulatory hepatology clinic
- Inclusion criteria for healthy volunteers:
- Signed informed consent after being informed
- Age 18-60 years
- Exclusion criteria for FGID patients:
- Inflammatory bowel disease
- Gastrointestinal malignancy
- Celiac Disease
- Known or suspected non-compliance, drug or alcohol abuse
- Previous large abdominal surgery likely to impact patient symptomatology
- Inability to follow the procedures of the study, e.g. due to language problems, dementia, etc. of the participant
- Previous enrollment into the current study
- Use of antibiotics in the previous 4 weeks before enrolment
- Exclusion criteria for hepatology control cohort:
- Previous diagnosed functional gastrointestinal disorders
- Exclusion criteria for healthy volunteers:
- Previous diagnosed functional gastrointestinal disorders
Exclusion
Key Trial Info
Start Date :
July 7 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 20 2024
Estimated Enrollment :
498 Patients enrolled
Trial Details
Trial ID
NCT03460613
Start Date
July 7 2017
End Date
March 20 2024
Last Update
December 2 2025
Active Locations (1)
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1
UniversitätsSpital
Zurich, Switzerland, 8091