Status:
COMPLETED
Modulation of Cognitive Flexibility by Tyrosine Depletion and Transcranial Direct Current Stimulation
Lead Sponsor:
Sheffield Hallam University
Conditions:
Cognitive Flexibility
Eligibility:
All Genders
18-30 years
Phase:
NA
Brief Summary
The dorsolateral prefrontal cortex (dlPFC) and dopamine (DA) have been implicated in the control of cognitive flexibility. However, while a great deal of what it is know regarding a causative relation...
Eligibility Criteria
Inclusion
- Either male or female
- You are aged between 18 and 30 years
- You are in good health
- You agree to fast overnight prior to testing
Exclusion
- Are suffering from cardiac, hepatic, renal, or neurological disorders
- Damaged or diseased skin on your face and scalp, or a sensitive scalp
- A history of alcohol or drug addiction, or severe psychiatric illness
- Are in drug treatment which may lower seizure threshold (i.e. epilepsy)
- You are pregnant
- Slept less than 6 hours prior to coming to the lab
- Suffer from phenylketonuria
- A history of or current experience of migraine or headaches
- A history of or current use of antidepressants
- A history of or current use of tyrosine supplements
- Consume more than five beverages containing caffeine per day
Key Trial Info
Start Date :
February 12 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2018
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT03462303
Start Date
February 12 2018
End Date
June 30 2018
Last Update
September 11 2018
Active Locations (1)
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1
Department of Psychology labs
Sheffield, South Yorkshire, United Kingdom, S10 2BQ