Status:
COMPLETED
Neoadjuvant Therapy for Esophageal Cancer and Cardiopulmonary Physiology
Lead Sponsor:
St. James's Hospital, Ireland
Conditions:
Esophageal Cancer
Radiation Pneumonitis
Eligibility:
All Genders
18+ years
Brief Summary
Although recent global trends indicate reduced postoperative mortality after esophagectomy, major morbidity, in particular pulmonary, remains high, with considerable health and economic costs. In a re...
Eligibility Criteria
Inclusion
- Locally advanced esophageal cancer undergoing multimodal therapy with curative intent at study centre during study period
- Pulmonary function assessed at a minimum of one preoperative timepoint
Exclusion
- Salvage, palliative or emergency surgery
Key Trial Info
Start Date :
January 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2018
Estimated Enrollment :
384 Patients enrolled
Trial Details
Trial ID
NCT03462524
Start Date
January 1 2010
End Date
January 1 2018
Last Update
March 12 2018
Active Locations (2)
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1
Department of Surgery, St. James's Hospital
Dublin, Ireland, D4
2
Wellcome Trust-Health Research Board Clinical Research Facility, St. James's Hospital
Dublin, Ireland, D8