Status:
COMPLETED
Expiratory Flow Limitation Assessment
Lead Sponsor:
Hospices Civils de Lyon
Conditions:
Acute Respiratory Distress Syndrome
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study intended to assess the expiratory flow limitation (EFL) during tidal breath in patients intubated in intensive care unit (ICU) for moderate or severe acute respiratory distress syndrome (AR...
Eligibility Criteria
Inclusion
- 18 years or more in age
- moderate to severe ARDS according to the Berlin definition : Intubated (or tracheotomized) and mechanically ventilated in the ICU
- no pregnancy
- informed consent from the next of kin
Exclusion
- Contra-indication to PEP \> 5 cmH2O
- extracorporeal membrane oxygenation (ECMO)
- chest tube
- mean arterial pressure \< 65 mmHg
- Contra-indication to oesophageal device
- underlying disease fatal in less than one year
- active therapy limitation
- under guardian
- refusal to participate
- not affiliated to insurance regimen
- speaking barrier of the next of kin
- investigator not available
Key Trial Info
Start Date :
February 5 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 2 2019
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT03462849
Start Date
February 5 2018
End Date
May 2 2019
Last Update
December 5 2025
Active Locations (2)
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1
CHU Grenoble Alpes
Grenoble, France
2
Hôpital de la Croix Rousse
Lyon, France, 69004