Status:
COMPLETED
Pain Inhibition and Facilitation in Recurrent Low Back Pain
Lead Sponsor:
Aalborg University
Conditions:
Recurrent Low Back Pain
Healthy
Eligibility:
All Genders
18-60 years
Brief Summary
This study evaluates psychophysical measures of pain inhibition and facilitation, along with cortical responses to different sensory stimuli, in patients with recurrent low back pain and matched healt...
Detailed Description
Pain inhibitory and facilitatory mechanisms have been suggested to play a role in the development of persistent low back pain; however, there is still debate on when changes in these mechanisms occur....
Eligibility Criteria
Inclusion
- Inclusion:
- Healthy men and women
- Aged 18-60 years
- No previous back pain OR \>1 previous episode of low back pain in past 12 months
- No current back pain OR Pain in the region posteriorly between the inferior border of the 12th rib and the lower gluteal fold (low back pain) at time of recruitment lasting \>24 hours
- Able to speak, read and understand English
- Exclusion:
- Pregnancy
- First episode of low back pain
- Low back pain associated with menstruation
- Chronic low back pain (continuous pain episode for \>3 months)
- Currently seeking active treatment for low back pain
- Red flags symptoms
- Drug addiction defined as the use of cannabis, opioids or other drugs
- Current or previous neurologic, musculoskeletal, mental, or other illnesses which may affect the trial
- Current or previous chronic or recurrent pain condition other than low back pain
- Current regular use of analgesic or other medication which may affect the trial
- Lack of ability to cooperate
- Recent history of acute pain particularly in the lower limbs (unless related to LBP)
- Abnormally disrupted sleep in 24 hours preceding experiment
Exclusion
Key Trial Info
Start Date :
April 10 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 14 2019
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03463759
Start Date
April 10 2018
End Date
December 14 2019
Last Update
December 11 2020
Active Locations (1)
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1
CNAP, SMI, Aalborg University
Aalborg, Denmark, 9000