Status:
COMPLETED
Spinal and Supra-Spinal Pain Mechanisms in Patients With Fibromyalgia
Lead Sponsor:
University of Florida
Conditions:
Fibromyalgia
Pain
Eligibility:
All Genders
18-65 years
Brief Summary
Fibromyalgia (FM) patients have increased windup (WU). However, WU of FM patients is only quantitatively but not qualitatively different from healthy controls (HC). Thus WU abnormalities of FM patient...
Detailed Description
The study team hypothesizes that at baseline the slopes of sensitivity adjusted WU of FM patients are not statistically different from HC. However, after capsaicin application, the slopes of sensitivi...
Eligibility Criteria
Inclusion
- individuals diagnosed with fibromyalgia will have pain of duration \> 6 months and meeting the 1990 Research Diagnostic Criteria for FM (ACR).
- healthy, pain-free age matched controls without chronic pain
Exclusion
- Allergy to red chili peppers;
- Pregnant;
- Significant hearing loss;
- Presence of chronic disease (e.g. cancer, cardiovascular disease, liver disease, kidney disease, diabetes, etc.).
- FM patients must be willing to discontinue or hold their FM related medications for at least 5 half-lives.
Key Trial Info
Start Date :
July 5 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 8 2023
Estimated Enrollment :
55 Patients enrolled
Trial Details
Trial ID
NCT03464292
Start Date
July 5 2018
End Date
December 8 2023
Last Update
December 14 2023
Active Locations (1)
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1
University of Florida
Gainesville, Florida, United States, 32610