Status:

COMPLETED

The Effect of Macronutrients on Satiety and Gut Hormone Responses

Lead Sponsor:

Imperial College London

Conditions:

Eating Behavior

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

This study is part of a research theme aiming at elucidating the physiological mechanisms of action of weight loss after gastric bypass surgery. The Roux-en-Y Gastric Bypass procedure induces pronounc...

Detailed Description

Ten healthy volunteers, aged 18 to 65 years will be recruited. Each subject will be studied on six occasions one week apart. On each visit, a baseline serum sample will be drawn from each subject. In ...

Eligibility Criteria

Inclusion

  • 18-65 years
  • Normal fasting glucose
  • Stable body weight for at least last three months
  • BMI \< 30 Kg/m2
  • Capacity to consent to participate
  • Independently mobile

Exclusion

  • Patients who meet any of the following criteria will be excluded:
  • Pre-diabetes Diabetes
  • Obesity
  • Smoking
  • Substance abuse
  • Pregnancy
  • Use of medications (except for oral contraceptives)
  • Chronic medical or psychiatric illness
  • Any significant abnormalities detected on physical examination, electrocardiography, or screening blood tests (measurement of complete blood count, electrolytes, fasting glucose, and liver function)

Key Trial Info

Start Date :

March 15 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2019

Estimated Enrollment :

8 Patients enrolled

Trial Details

Trial ID

NCT03466047

Start Date

March 15 2018

End Date

January 1 2019

Last Update

October 20 2020

Active Locations (1)

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Clinical Research Centre

Dublin, Ireland, Dublin 4