Status:
COMPLETED
Hyperbaric Oxygen Therapy for Adult Onset Post Traumatic Stress Disorder
Lead Sponsor:
Assaf-Harofeh Medical Center
Conditions:
Ptsd
Eligibility:
MALE
25-60 years
Phase:
NA
Brief Summary
Posttraumatic stress disorder (PTSD) is the long term effect of severely distressing traumatic event characterized by intrusive thoughts, nightmares, and avoidance. Brain imaging of PTSD patients demo...
Detailed Description
Posttraumatic stress disorder (PTSD) has been described as "the complex somatic, cognitive, affective, and behavioral effects of psychological trauma". PTSD is triggered by a severe distressing trauma...
Eligibility Criteria
Inclusion
- Adult onset PTSD, defined by DSM-V criteria, as a result of combat or a terror- related event.
- Age 25-60 years, 4-years or more from the traumatic event and failure to improve with at least one line of conventional treatment.
Exclusion
- A history of traumatic brain injury, epilepsy, a brain tumor; skull base fractures or neurosurgery.
- Severe substance use disorders a current manic episode, psychotic disorders or serious suicidal ideation at baseline.
- Major cognitive deficits
- History of HBOT for any reason, prior to study enrollment.
- Chest pathology incompatible with pressure changes (including active asthma).
- Inner ear disease.
- The inability to perform an awake brain MRI test.
- Inability to provide informed consent
Key Trial Info
Start Date :
March 4 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 20 2019
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03466554
Start Date
March 4 2018
End Date
September 20 2019
Last Update
July 3 2024
Active Locations (1)
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1
Assaf-Harofeh Medical Center
Ẕerifin, Israel, 70300