Status:

COMPLETED

Role of Interferon-λ and Vaccine Response

Lead Sponsor:

University Hospital, Basel, Switzerland

Conditions:

Vaccine Response Impaired

Allogeneic Stem Cell Transplantation

Eligibility:

All Genders

18+ years

Brief Summary

The following observational study will investigate whether the vaccine response (antibodies, T and B cells) after allogeneic stem cell transplantation is influenced by genetic polymorphisms in the int...

Detailed Description

The research project deals with one of the most important virological preventive measures after stem cell transplantation: vaccination against influenza viruses. Patients with allogeneic stem cell tra...

Eligibility Criteria

Inclusion

  • held allogeneic stem cell transplantation over 1 year ago

Exclusion

  • Known vaccine intolerance (e.g. Protein allergy or severe vaccine-associated side effects, e.g. Guillian Barré syndrome)

Key Trial Info

Start Date :

September 1 2014

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2017

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT03467074

Start Date

September 1 2014

End Date

December 31 2017

Last Update

October 17 2019

Active Locations (1)

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Department of Clinical Microbiology

Basel, Switzerland, 4031