Status:

COMPLETED

Signaling Pathways Targeting Colorectal Cancer in Egypt

Lead Sponsor:

Assiut University

Conditions:

Colorectal Cancer

Eligibility:

All Genders

Brief Summary

Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the second leading cause of cancer-related death worldwide. In Egypt, CRC constitutes 4.2% of all cancers with median age is 50 ...

Detailed Description

The TP53-induced glycolysis and apoptosis regulator (TIGAR) is a transcriptional target of p53. TIGAR functions as a fructose-2,6-bisphosphatase, decreasing the flux through the main glycolytic pathwa...

Eligibility Criteria

Inclusion

  • All Patients confirmed histopathologically to have early stages of colorectal cancer.
  • Risky group patients (including those with ulcerative colitis, chron's disease, familial adenomatous polyposis).

Exclusion

  • Patients with previous history of CRC treated with chemotherapy or presence of other types of cancer.

Key Trial Info

Start Date :

March 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 1 2020

Estimated Enrollment :

180 Patients enrolled

Trial Details

Trial ID

NCT03467308

Start Date

March 1 2018

End Date

April 1 2020

Last Update

May 11 2020

Active Locations (1)

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1

Assiut University- faculty of medicine -Medical biochemistry department

Asyut, Egypt, 71111