Status:

SUSPENDED

Bronchial Dilation Test in Wheezy Infants

Lead Sponsor:

Guangzhou Institute of Respiratory Disease

Collaborating Sponsors:

Firestone Institute for Respiratory Health

Conditions:

Asthma

Eligibility:

All Genders

5-36 years

Brief Summary

The purpose of the study is to establish the methodology of bronchial dilation test by salbutamol MDI with Spacer in wheezy infants with asthma and to evaluate the effects of atopy on the exacerbation...

Detailed Description

After screening,each participant undergo baseline pulmonary function test(Jaeger Master Screen Baby Body, Germany)and post-bronchodilator measurements that performed 10min after 200ug of salbutamol ad...

Eligibility Criteria

Inclusion

  • normal term infants.Recurrent wheezing with or without atopy,none of the subjects had a history of respiratory illness, congenital heart disease,dysphagia,oxygen saturation≤90% on room air,an active seizure disorder,or upper airway obstruction,or requirement for assisted ventilation in the neonatal periods,all infants were asymptomatic for at least 2 weeks preceding the test.

Exclusion

  • subjects had a history of respiratory illness, congenital heart disease,dysphagia,oxygen saturation≤90% on room air,an active seizure disorder,or upper airway obstruction,;all infants were asymptomatic for at least 2 weeks preceding the test.

Key Trial Info

Start Date :

July 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2019

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT03467776

Start Date

July 1 2018

End Date

December 1 2019

Last Update

March 16 2018

Active Locations (1)

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Page 1 of 1 (1 locations)

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State Key Laboratory of Respiratory Disease;China Clinical Research Center of Respiratory Disease;First Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, China, 510120