Status:
COMPLETED
Medication Optimization Using Pharmacogenetic Testing and the G-DIG to Reduce Polypharmacy in a Mental Health Population
Lead Sponsor:
Seattle Institute for Biomedical and Clinical Research
Collaborating Sponsors:
Genomind, LLC
Conditions:
Pharmacogenetic Testing
Eligibility:
All Genders
18-75 years
Brief Summary
Use of polypharmacy has significantly increased over the past two decades, which has unproven clinical benefit and is associate with an increased the risk of adverse side effects. Pharmacogenetic assa...
Detailed Description
Use of polypharmacy has significantly increased over the past two decades, which has unproven clinical benefit and increased the risk of drug-drug interactions and adverse side effects. Pharmacogeneti...
Eligibility Criteria
Inclusion
- Currently receiving outpatient care for mental health diagnosis at VA Puget Sound Health Care System (VA PSHCS) and referred by sub-investigator on listed for study
- Currently experiencing a sub-optimal medication response as assessed by either continue symptoms or medication side effects; which in the opinion of their treating provider would indicate or warrant a change in medications
- Currently prescribed at least five medications; two being for a mental health diagnosis OR one mental health medication prescribed for mental health diagnosis and one for mediating side effects related to the medication prescribed for the mental health diagnosis.
- Between the ages of 18-75.
Exclusion
- Any mental health or physical health diagnosis, which in the opinion of their treating prescriber would prevent them from being compliant on a medication regimen or being able to complete the study measures.
- Current/active diagnosis of severe alcohol or drug use disorder
- Serious medical or mental health symptoms requiring immediate stabilization and/or hospitalization
- Impaired decision making capacity that in the clinical judgment of their provider would affect their ability to provide informed consent
- Self-identification as being current pregnancy
Key Trial Info
Start Date :
January 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 17 2024
Estimated Enrollment :
53 Patients enrolled
Trial Details
Trial ID
NCT03468309
Start Date
January 1 2018
End Date
April 17 2024
Last Update
April 23 2024
Active Locations (1)
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1
VA Puget Sound Health Care System
Tacoma, Washington, United States, 98493