Status:
COMPLETED
Duloxetine for Acute Post-mastectomy Pain
Lead Sponsor:
Assiut University
Conditions:
Acute Pain
Eligibility:
FEMALE
20-70 years
Phase:
NA
Brief Summary
The objective of this study is to evaluate the analgesic effect of oral dulexitine tablet (administered 2 h before surgery) as well as the ideal dose for acute postmastectomy pain.
Detailed Description
patients undergoing mastectomy with axillary evacuation will be divided to four groups, Placebo group: received placebo capsule Duloxetine 30: received duloxetine 30 mg capsule Duloxetine 60: received...
Eligibility Criteria
Inclusion
- Adult females scheduled for unilateral MRM with axillary evacuation for breast cancer,
- American Society of Anesthesiologists physical status (ASA) class I and II
Exclusion
- Patients with a known allergy to Duloxetine or morphine,
- A history of drug or alcohol abuse,
- Patients with impaired kidney or liver functions,
- Patients with chronic pain or regularly receiving analgesics,
- Any psychiatric illness that would interfere with the perception and the assessment of pain.
- Any reason that resulted in the protocol violation.
Key Trial Info
Start Date :
April 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 10 2020
Estimated Enrollment :
88 Patients enrolled
Trial Details
Trial ID
NCT03468348
Start Date
April 1 2018
End Date
February 10 2020
Last Update
June 24 2020
Active Locations (1)
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1
Diab
Asyut, Assuit, Egypt, 71515