Status:
COMPLETED
The Study of Effectiveness of rTMS on Rumination and Anhedonia in Patients With Major Depressive Disorder
Lead Sponsor:
University of Tehran
Collaborating Sponsors:
Stanford University
Conditions:
Major Depressive Disorder
Bipolar Depression
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Rumination is significantly frequent in major depressive disorder. However, not a lot of studies have investigated the effects of repetitive transcranial magnetic stimulation on rumination and its ele...
Detailed Description
This study aims to compare the effect of unilateral and bilateral rTMS on the reduction of rumination and anhedonia and their associated neural networks. In a randomized double-blind trial, 65 patient...
Eligibility Criteria
Inclusion
- Outpatients male and female with the range of 18-65 years of age
- The diagnosis of Major depressive disorder according to DSM-V
- Having BDI\>18
- Having stable symptoms as defined by not requiring a change in medication for at least 4 weeks
- Completion of consent form
- Being under supervision of a psychiatrist
Exclusion
- The history of rTMS treatment for any reason
- Cardiac pacemaker
- The risk of seizure with any reasons
- Pregnancy
- High risk of suicide
- Intracranial implant and other ferromagnetic materials close to the head
Key Trial Info
Start Date :
December 21 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 30 2020
Estimated Enrollment :
61 Patients enrolled
Trial Details
Trial ID
NCT03468686
Start Date
December 21 2016
End Date
October 30 2020
Last Update
October 5 2022
Active Locations (1)
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1
Atieh Clinical Neuroscience Center (ACNC)
Tehran, Iran, 1969713663