Status:
COMPLETED
High Protein Intake and Early Exercise in Adult Intensive Care Patients
Lead Sponsor:
Hospital Sao Domingos
Conditions:
Critically Ill Patients
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study analyse the impact of high protein intake associated to early programed exercise on functional outcomes of adult intensive care patients.
Detailed Description
The muscle weakness associated to intensive care, one of the components of Post Intensive Care Syndrome (PICS) has a significant impact on the short-term and long-term outcomes in the critically ill p...
Eligibility Criteria
Inclusion
- We will include 180 consecutive patients admitted to one of the study ICUs
- Aged 18 years or above.
- Non-pregnant.
- Requiring mechanical ventilation for at least 48 hours.
- Expected ICU stay higher than 3 days.
Exclusion
- Inability to walk without assistance before the acute illness that led to ICU admission (use of gait aid is not an exclusion criterion).
- Cognitive impairment prior to hospitalization described by relatives and evaluated by the ICU psychology team.
- Neuromuscular diseases that compromise weaning from mechanical ventilation.
- Acute pelvic fracture.
- Unstable spinal cord trauma.
- Patients considered moribund.
- In some situations patients will not be included in the resistive exercise program for as long as a temporary limiting factor remains:
- Patients undergoing neuromuscular blocking drugs.
- Patients under high-dose vasoactive drug use.
- Mechanical ventilation with FIO2 (fraction of inspired oxygen) ≥ 60% and / or PEEP (positive end-expiratory pressure)\> 12 cm H2O.
- Intracranial hypertension.
- . Open abdomen.
- Status epilepticus.
Key Trial Info
Start Date :
June 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 31 2020
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT03469882
Start Date
June 1 2018
End Date
July 31 2020
Last Update
July 30 2021
Active Locations (1)
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1
Icu Hospital Sao Domingos
São Luís, Maranhão, Brazil, 65060-645