Status:
UNKNOWN
Relation of Epicardial Fat and Diabetic Nephropathy in Egyptian Patients
Lead Sponsor:
Assiut University
Conditions:
Type2 Diabetes Mellitus
Eligibility:
All Genders
30-65 years
Brief Summary
The heart and vessels are surrounded by layers of adipose tissue, which is a complex organ composed of adipocytes, stromal cells, macrophages, and a neuronal network, all nourished by a rich microcirc...
Detailed Description
The epicardial fat layer originates from mesothelial cells and hence obtains its vascular supply from the coronary arteries. Much of the importance within the epicardial fat is its anatomical closenes...
Eligibility Criteria
Inclusion
- All patients attends to internal medicine, cardiology or nephrology outpatient clinics with the following criteria:
- Patients who are older than 30.
- Patients who are younger than 65.
- Patients with type 2 diabetes milletus.
- Patients with renal complaints (loin pain, frequency, ….).
- No sex predilection.
Exclusion
- Age:
- Patients who are less than 30 years or more than 65 years.
- Patients with type 1 diabetes milletus or diabetes insipidus. 3. Patients with cardiac diseases: A. Patients with cardiac diseases ( coronary artery disease, heart failure, myocardial infarction, infection,…) or history of cardiac problem or previous intervention (PCI,..) will be excluded from our study.
- B. Patients with cardiac congenital anomalies. 4. Patients with active infections. 5- Patients with autoimmune diseases: As rheumatoid arthritis or systemic lupus. 6- Patients with acute diabetic complications. 7- Patients with a family history of kidney failure. 8- Patients with other causes of nephropathy will be excluded as: A. Liver cirrhosis to exclude hepatorenal syndrome. B. Autoimmune diseases as lupus nephritis. C. History of excessive analgesics intake. D. End stage kidney disease (chronic renal failure on dialysis).
Key Trial Info
Start Date :
May 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2019
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03470415
Start Date
May 1 2018
End Date
December 1 2019
Last Update
March 20 2018
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