Status:
COMPLETED
Neuropsychological Management of Multiple Sclerosis: Benefits of a Computerised Semi-autonomous At-home Cognitive Rehabilitation Programme
Lead Sponsor:
University Hospital, Caen
Conditions:
Relapsing Remitting Multiple Sclerosis
Secondary Progressive Multiple Sclerosis
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Multiple sclerosis (MS) is a central nervous system inflammatory disease that causes a chronic and progressive physical handicap. Though primarily considered as a motor disease, it may, in 40 to 65% o...
Eligibility Criteria
Inclusion
- MS defined according to the McDonald criteria revised in 2010
- Men and women aged between 18 and 65 years
- RR and SP forms
- Duration of progression ≤ 25 years
- EDSS ≤ 5.5
- Lack of disease activity as defined by the new Lublin criteria (2013)
- Cognitive complaint and/or cognitive disorders according to the investigator's judgement
- Impaired cognitive performance at least 1.65 SD below normative data at one test of the BCcogSEP battery
- French native language
- Owner of a laptop computer with Internet access
- Signing of the informed consent
Exclusion
- \- Other neurological, psychiatric or developmental diseases prior to the MS diagnosis
- Cranial trauma sequelae
- Chronic alcohol and/or drug consumption
- EDSS \> 6
- Relapse and/or treatment with corticosteroids within the past month
- Persons deprived of liberty, minors, adults under wardship
- Cognitive examination within the past 6 months (including in particular all or some of the tests proposed by this project)
- Presence of dementia according to DSM V criteria, or of cognitive disorders preventing the patient from undergoing cognitive tests or performing cognitive rehabilitation exercises
- Any visual or motor deficit preventing the patient from undergoing cognitive tests or performing cognitive rehabilitation exercises
Key Trial Info
Start Date :
October 31 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 31 2024
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03471338
Start Date
October 31 2017
End Date
May 31 2024
Last Update
July 25 2025
Active Locations (1)
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1
University Hospital of Caen
Caen, Calvados, France, 14000