Status:

COMPLETED

Intensity Modulated Radiotherapy With Concomitant Boost in Breast Cancer

Lead Sponsor:

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Conditions:

Breast Cancer

Radiation Toxicity

Eligibility:

FEMALE

Brief Summary

To assess feasibility of postoperative IMRT with concomitant boost in moderate-high risk breast cancer in terms of late toxicity and local control

Detailed Description

Patients treated conservatively with moderate-high risk breast cancer were treated with IMRT plus concomitant boost to surgical bed (up to a dose of 50 Gy to whole breast and 60 Gy to the tumor bed). ...

Eligibility Criteria

Inclusion

  • histologically confirmed invasive breast cancer (pT1-4) with at least one of these characteristics: 3 or more metastatic axillary nodes, pre or peri-menopausal status, close resection margins
  • breast conservative surgery

Exclusion

  • positive margins
  • distant metastases

Key Trial Info

Start Date :

June 1 2001

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2017

Estimated Enrollment :

451 Patients enrolled

Trial Details

Trial ID

NCT03471741

Start Date

June 1 2001

End Date

December 31 2017

Last Update

March 21 2018

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